Audio Laser Clinic

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Scientific references

The below listed scientific references are the base for the treatment methods used at the Audio Laser Clinic. Both the treatment methods LASER and PEMF/rTMS are based upon a scientific ground including positive, double blind, randomized studies. For PEMF/rTMS therapy for tinnitus and many other disorders evidence occurs. For the treatment of tinnitus using LASER therapy there are several so called gold standard studies (peer reviewed, published, prospective, randomized, placebo controlled, double blind positive studies). Gold standard studies have the highest achievable scientific level and constitute the best foundation for evidence based medicine.

Evidence for PEMF/rTMS-treatment of inner ear disorders
The method has evidence for the treatment of tinnitus, pain and many more disorders

  1. Lefaucheur JP, André-Obadia N, Antal A, Ayache SS, Baeken C, Benninger DH, Cantello RM, Cincotta M, de Carvalho M, De Ridder D, Devanne H, Di Lazzaro V, Filipović SR, Hummel FC, Jääskeläinen SK, Kimiskidis VK, Koch G, Langguth B, Nyffeler T, Oliviero A, Padberg F, Poulet E, Rossi S, Rossini PM, Rothwell JC, Schönfeldt-Lecuona C, Siebner HR, Slotema CW, Stagg CJ, Valls-Sole J, Ziemann U, Paulus W, Garcia-Larrea L. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin Neurophysiol. 2014 Nov;125(11):2150-206. doi:  10.1016/j.clinph.2014.05.021. Epub 2014 Jun 5. PMID: 25034472 [PubMed - in process].

MEDLINE indexed scientific support for LASER treatment
of the inner ear and its diseases and disorders

  1. Intravenous laser irradiation of blood for the combined treatment of patients presenting with chronic sensorineural hearing loss. Vestn Otorinolaringol. 2011;(2):43-5. PMID: 21512485 [PubMed - indexed for MEDLINE].

  2. Belkahia A. Ann Otolaryngol Chir Cervicofac. 1971 Sep;88(9):467-73. Biological effects of laser beams in otolaryngology. Medical application approach. French. PMID: 5122192 [PubMed - indexed for MEDLINE].

  3. Bogomil'skiĭ MR, Fitenko LN, D'iakonova IN, Tikhomirov AM, Minasian VS. Effect of low-energy laser irradiation on the functional state of the acoustic analyzer (experimental study). Vestn Otorinolaringol. 1989 Mar-Apr;(2):29-34. Russian. PMID: 2728175 [PubMed - indexed for MEDLINE]

  4. Bykov VL, Martyniuk LA. Low-energy laser irradiation in the complex treatment of patients with ear diseases. Vopr Kurortol Fizioter Lech Fiz Kult. 1985 Mar-Apr;(2):60-2. Russian. PMID: 4013119 [PubMed - indexed for MEDLINE]

  5. Cuda D, De Caria A. Effectiveness of combined counseling and low-level laser stimulation in the treatment of disturbing chronic tinnitus. Int Tinnitus J. 2008;14(2):175-80. PMID: 19205171 [PubMed - indexed for MEDLINE]

  6. Dejakum K, Piegger J, Plewka C, Gunkel A, Thumfart W, Kudaibergenova S, Goebel G, Kral F, Freysinger W. Medium-level laser in chronic tinnitus treatment. Biomed Res Int. 2013;2013:324234. doi: 10.1155/2013/324234. Epub 2013 Nov 5. PMID: 24294604 [PubMed - indexed for MEDLINE]

  7. Djalilian HR, Lee AD. Stapedotomy using continuous wave diode laser (808 nm). Otol Neurotol. 2008 Dec;29(8):1215; author reply 1215-6. No abstract available. PMID: 18716564 [PubMed - indexed for MEDLINE]

  8. Flock A, Flock B, Scarfone E. Laser scanning confocal microscopy of the hearing organ: fluorochrome-dependent cellular damage is seen after overexposure. J Neurocytol. 1998;27(7):507-16. PMID: 11246490 [PubMed - indexed for MEDLINE]

  9. Fridberger A, Ren T. Local mechanical stimulation of the hearing organ by laser irradiation. Neuroreport. 2006 Jan 23;17(1):33-7. PMID: 16361946 [PubMed - indexed for MEDLINE]

  10. Gogeliia AI, Chabashvili NM, Matiashvili MK, Kasradze PA. Experience on treatment of children with otorhinolaryngological diseases by low intensity laser irradiation. Georgian Med News. 2006 Jan;(130):84-6. Russian. PMID: 16510921 [PubMed - indexed for MEDLINE]

  11. Gungor A, Dogru S, Cincik H, Erkul E, Poyrazoglu E. Effectiveness of transmeatal low power laser irradiation for chronic tinnitus. J Laryngol Otol. 2008 May;122(5):447-51. Epub 2007 Jul 12. PMID: 17625032 [PubMed - indexed for MEDLINE]

  12. Hahn A, Sejna I, Stolbova K, Cocek A. Combined laser-EGb 761 tinnitus therapy.
    Acta Otolaryngol Suppl. 2001;545:92-3. PMID: 11677752 [PubMed - indexed for MEDLINE]

  13. Hahn A, Radkova L, Achiemere G, Klement V, Alpini D, Strouhal. Multimodal therapy for chronic tinnitus. J. Int Tinnitus J. 2008;14(1):69-72. PMID: 18616089 [PubMed - indexed for MEDLINE]

  14. Hubácek J, Hlozek Z, Prucek I. Experience with the He-Ne laser in otorhinolaryngology. Cesk Otolaryngol. 1984 Jun;33(3):135-9. Czech. No abstract available. PMID: 6498995 [PubMed - indexed for MEDLINE]

  15. Izzo AD, Richter CP, Jansen ED, Walsh JT Jr. Laser stimulation of the auditory nerve.
    Lasers Surg Med. 2006 Sep;38(8):745-53. PMID: 16871623 [PubMed - indexed for MEDLINE]

  16. Izzo AD, Suh E, Pathria J, Walsh JT, Whitlon DS, Richter CP. Selectivity of neural stimulation in the auditory system: a comparison of optic and electric stimuli. J Biomed Opt. 2007 Mar-Apr;12(2):021008. PMID: 17477715 [PubMed - indexed for MEDLINE]

  17. Izzo AD, Walsh JT Jr, Jansen ED, Bendett M, Webb J, Ralph H, Richter CP. Optical parameter variability in laser nerve stimulation: a study of pulse duration, repetition rate, and wavelength. IEEE Trans Biomed Eng. 2007 Jun;54(6 Pt 1):1108-14. PMID: 17554829 [PubMed - indexed for MEDLINE]

  18. Izzo AD, Walsh JT Jr, Ralph H, Webb J, Bendett M, Wells J, Richter CP. Laser stimulation of auditory neurons: effect of shorter pulse duration and penetration depth. Biophys J. 2008 Apr 15;94(8):3159-66. Epub 2008 Jan 11. PMID: 18192375 [PubMed - indexed for MEDLINE]

  19. Jung JY, Kwon PS, Ahn JC, Ge R, Suh MW, Rhee CK. In vitro and in vivo photodynamic therapy of otitis media in gerbils. Laryngoscope. 2009 Sep;119(9):1781-7. PMID: 19572273 [PubMed - indexed for MEDLINE]

  20. Kharaishvili G, Gogeliia A. Changes of blood paramagnetic centres of animals irradiated with low-intensity laser. Georgian Med News. 2006 Apr; (133): 108-110. Russian. PMID: 16705246 [PubMed - indexed for MEDLINE]

  21. Lapchenko AS. Current potentialities of laser radiation in otorhinolaryngological practice. Vestn Otorinolaringol. 2006;(5):59-62. Review. Russian. PMID: 17278698 [PubMed - indexed for MEDLINE]

  22. Lapchenko AS, Gedzik VA. Use of semiconductor laser in the treatment of various inflammatory ORL diseases. Vestn Otorinolaringol. 1991 Sep-Oct;(5):14-6. Russian. PMID: 1755176 [PubMed - indexed for MEDLINE]

  23. Lapchenko AS. Low-energy laser radiation in otorhinolaryngology: history and current opportunities. Vestn Otorinolaringol. 2002;(4):51-4. Review. Russian. PMID: 12400143 [PubMed - indexed for MEDLINE]

  24. Lapchenko AS, Kucherov AG, Levina IuV, Ivanets IV, Krasiuk AA, Kadymova MI. The application of supravascular laser irradiation of blood for the treatment of cochleovestibular disorders. Vestn Otorinolaringol. 2011;(1):39-40. PMID: 21378736 [PubMed - indexed for MEDLINE]

  25. Lin SZ, Fan JP, Sun AH, Guan J, Liu HB, Zhu QB. J Laryngol Otol. 2010 May;124(5):e5. Epub 2009 Oct 20. Efficacy of laser occlusion of posterior semicircular canal for benign paroxysmal positional vertigo: case report. PMID: 19840431 [PubMed - indexed for MEDLINE]

  26. Littlefield PD, Vujanovic I, Mundi J, Matic AI, Richter CP. Laser stimulation of single auditory nerve fibers. Laryngoscope. 2010 Oct;120(10):2071-82. PMID: 20830761 [PubMed - indexed for MEDLINE]

  27. Markaryan A, Nelson EG, Hinojosa R. Major arc mitochondrial DNA deletions in cytochrome c oxidase-deficient human cochlear spiral ganglion cells. Acta Otolaryngol. 2010 Jul;130(7):780-7. PMID: 20085441 [PubMed - indexed for MEDLINE]

  28. Mishen'kin NV, Tikhomirov VV, Krotov IuA, Konev VP. Laser therapy in the early postoperative period following sanitizing surgery of the ear using a closed method (experimental study). Vestn Otorinolaringol. Russian. 1988 Nov-Dec;(6):75-6. PMID: 3227631 [PubMed - indexed for MEDLINE]

  29. Mishen'kin NV, Tikhomirov VV, Krotov IuA. Effects of helium-neon laser energy on the tissues of the middle ear in the presence of biological fluids and drug solutions. Vestn Otorinolaringol. 1990 Sep-Oct;(5):18-21. Russian. PMID: 2267687 [PubMed - indexed for MEDLINE]

  30. Mishen'kin NV, Krotov IuA. Helium-neon lasers in clinical and experimental otology. Vestn Otorinolaringol. 1990 May-Jun;(3):71-7. Review. Russian. PMID: 2200197 [PubMed - indexed for MEDLINE]

  31. Mollasadeghi A, Mirmohammadi SJ, Mehrparvar AH, Davari MH, Shokouh P, Mostaghaci M, Baradaranfar MH, Bahaloo M. Efficacy of low-level laser therapy in the management of tinnitus due to noise-induced hearing loss: a double-blind randomized clinical trial. ScientificWorldJournal. 2013 Oct 28;2013:596076. doi: 10.1155/2013/596076. eCollection 2013. PMID: 24288494 [PubMed - indexed for MEDLINE]

  32. Pal'chun VT, Lapchenko AS, Kadymova MI, Kucherov AG. Low-energy laser radiation in the combined treatment of sensorineural hearing loss and Menière's disease. Vestn Otorinolaringol. 1996 Jan-Feb;(1):23-5. Russian. PMID: 8714046 [PubMed - indexed for MEDLINE]

  33. Pfeiffer N. Argon laser offers breakthrough in treating inner ear disorders. J Clin Laser Med Surg. 1992 Aug;10(4):311-3. PMID: 10147882 [PubMed - indexed for MEDLINE]

  34. Plath P, Olivier J. Results of combined low-power laser therapy and extracts of Ginkgo biloba in cases of sensorineural hearing loss and tinnitus. Adv Otorhinolaryngol. 1995;49:101-4. No abstract available. PMID: 7653339 [PubMed - indexed for MEDLINE]

  35. Pluzhnikov MS, Lopotko AI. Low-intensity laser irradiation in otorhinolaryngology. Vestn Otorinolaringol. 1996 Mar-Apr;(2):5-14. Russian. PMID: 8711850 [PubMed - indexed for MEDLINE]

  36. Pluzhnikov SM, Ivanov BS, Usanov AA, Glukhova EIu. Use of intracavitary low-energy laser therapy in the complex treatment of inflammatory diseases of the sphenoid sinus. Vestn Otorinolaringol. 1986 Jul-Aug;(4):72-3. Russian. No abstract available. PMID: 3750625 [PubMed - indexed for MEDLINE]

  37. Ribári O, Jóri J, Kiss JG, Vóna I, Tomity I. Closure of tympanic perforations with low-energy He- Ne-laser irradiation. Acta Chir Acad Sci Hung. 1980;21(3):229-38. German. PMID: 7324719 [PubMed - indexed for MEDLINE]

  38. Ribari O. The stimulating effect of low power laser rays : experimental examinations in otorhinolaryngology. Rev Laryngol Otol Rhinol (Bord). 1981 Nov-Dec;102(11-12):531-3. No abstract available. PMID: 7339757 [PubMed - indexed for MEDLINE]

  39. Sedlmaier B, Jovanovic S. Treatment of acute otitis media with the CO2 laser. HNO. 2000; 48 (8): 557-560. PMID: 10994164 [PubMed - indexed for MEDLINE]

  40. Shiomi Y, Takahashi H, Honjo I, Kojima H, Naito Y, Fujiki N. Efficacy of transmeatal low power laser irradiation on tinnitus: a preliminary report. Auris Nasus Larynx. 1997;24(1):39-42. PMID: 9148726 [PubMed - indexed for MEDLINE]

  41. Siedentopf CM, Ischebeck A, Haala IA, Mottaghy FM, Schikora D, Verius M, Koppelstaetter F, Buchberger W, Schlager A, Felber SR, Golaszewski SM. Neural correlates of transmeatal cochlear laser (TCL) stimulation in healthy human subjects. Neurosci Lett. 2007 Jan 16;411(3):189-93. Epub 2006 Nov 22. PMID: 17123710 [PubMed - indexed for MEDLINE]

  42. Svistushkin VM, Bezchinskaia MIa, Morozova SV, Makeeva NS. Use of helium-neon laser device LTM-01 in the treatment of patients with chronic suppurative otitis media. Vestn Otorinolaringol. 1992 Jan-Feb;(1):16-8. Russian. PMID: 1589937 [PubMed - indexed for MEDLINE]

  43. Tauber S, Baumgartner R, Schorn K, Beyer W. Lightdosimetric quantitative analysis of the human petrous bone: experimental study for laser irradiation of the cochlea. Lasers Surg Med. 2001;28(1):18-26. PMID: 11430438 [PubMed - indexed for MEDLINE]

  44. Tauber S, Schorn K, Beyer W, Baumgartner R. Transmeatal cochlear laser (TCL) treatment of cochlear dysfunction: a feasibility study for chronic tinnitus. Lasers Med Sci. 2003;18(3):154-61. PMID: 14505199 [PubMed - indexed for MEDLINE]

  45. Teggi R, Bellini C, Fabiano B, Bussi M. Efficacy of low-level laser therapy in Ménière's disease: a pilot study of 10 patients. Photomed Laser Surg. 2008 Aug;26(4):349-53. PMID: 18665761 [PubMed - indexed for MEDLINE]

  46. Teggi R, Bellini C, Piccioni LO, Palonta F, Bussi M. Transmeatal low-level laser therapy for chronic tinnitus with cochlear dysfunction. Audiol Neurootol. 2009;14(2):115-20. PMID: 18843180 [PubMed - indexed for MEDLINE]

  47. Teudt IU, Maier H, Richter CP, Kral A. Acoustic events and "optophonic" cochlear responses induced by pulsed near-infrared laser. IEEE Trans Biomed Eng. 2011 Jun;58(6):1648-55. Epub 2011 Jan 28. PMID: 21278011 [PubMed - indexed for MEDLINE]

  48. Timirgaleev M, Shuster M, Gavrilenko S. Transtubal laser therapy of inflammatory diseases of the eustachian tube and middle ear. Vestnik Otorinolaringol. 1986;(1):63-6. Russian. PMID: 3952933 [PubMed - indexed for MEDLINE]

  49. Wenzel GI, Pikkula B, Choi CH, Anvari B, Oghalai JS. Laser irradiation of the guinea pig basilar membrane. Lasers Surg Med. 2004;35(3):174-80. PMID: 15389736 [PubMed - indexed for MEDLINE]

  50. Wenzel GI, Anvari B, Mazhar A, Pikkula B, Oghalai JS. Laser-induced collagen remodeling and deposition within the basilar membrane of the mouse cochlea. J Biomed Opt. 2007 Mar-Apr;12(2):021007. PMID: 17477714 [PubMed - indexed for MEDLINE]

  51. Wenzel GI, Balster S, Zhang K, Lim HH, Reich U, Massow O, Lubatschowski H, Ertmer W, Lenarz T, Reuter G. Green laser light activates the inner ear. J Biomed Opt. 2009 Jul-Aug;14(4):044007. PMID: 19725719 [PubMed - indexed for MEDLINE]

  52. Zazzio M. Pain threshold improvement for chronic hyperacusis patients in a prospective clinical study. Photomed Laser Surg. 2010 Jun;28(3):371-7. PMID: 19821704 [PubMed - indexed for MEDLINE]

Non-MEDLINE indexed published scientific support for
LASER treatment of the inner ear and its diseases and disorders

  1. Beyer W, Baumgartner R, Tauber S. Dosimetric Analysis for Low-Level-Lasertherapy (LLLT) of the Human inner Ear. Proc BiOS Europe '98, 8-12 Sept 1998, Stockholm, Sweden.

  2. Beyer W, Baumgartner R, Tauber S. Dosimetric analysis for low-level-lasertherapy (LLLT) of the human inner ear at 593nm and 633nm. Proc. SPIE Vol. 3569, p. 56-59, Effects of Low-Power Light on Biological Systems IV, Giovanni F. Bottiroli; Tiina I. Karu; Rachel Lubart; Eds. (SPIE Homepage) Publication Date: Dec 1998.

  3. Backman M. LASER therapy in the combined treatment of hyperacusis, a prospective clinical study - a preliminary report from a clinical pilot study. Oral presentation, Neurootological and Equilibriometric Society, International Tinnitus Symposium, Prague, the Czech Republic, 30th March, 2004.

  4. Backman M. Hyperacusis Treatment with a Combination of Low Level Laser light, Anti-Oxidant Control and Pulsed Electromagnetic Field - A Clinical Pilot Study. Journal of Vestibular Research. 2004; (14) 2/3: 184.

  5. Backman M. Hyperacusis as a Treatment Modality. Otoneurological Days, Prague, March 2005.

  6. Backman M. LASER therapy in the combined treatment of hyperacusis, a prospective clinical study on 245 observations. Oral presentation at the LASER medical congress, LASER PRAHA, 17th September 2005, European Medical Laser Association, Prague, 2005.

  7. Dehkordi MA, Einolghozati S, Ghasemi SM, Abolbashari S, Meshkat M, Behzad H. Effect of low-level laser therapy in the treatment of cochlear tinnitus: A double-blind, placebo-controlled study. Ear Nose Throat J. 2015 Jan;94(1):32-6. PMID: 25606834 [PubMed - in process]

  8. Gable P. A pilot study on Low Level Laser Therapy (LLLT) for otitis externa - swimmers ear. Implications for competitive swimmers. Proc. WALT 2002, Tokyo, Japan, June 2002.

  9. Gogeliia A. Efficiency of Low Level Laser Therapy in Otology. Annals of Biomedical Research and Education , 2002 April/June, Volume 2, Issue 2, 151-153.

  10. Hahn A. Combined tinnitus therapy with soft laser and EGb 761. Oral presentation at Bárány Society Meeting in Bell Harbor International Conference Center, Seattle, Washington State, USA. September 26-29, 2002.

  11. Hahn A, Schalek P, Sejna I, Rosina J. Combined tinnitus therapy with laser and EGb 761: further experiences. Int Tinnitus J. 2012;17(1):47-50. PMID: 23906827 [PubMed - in process]

  12. Hubacek J. Our Experience with CO2 and He-Ne Lasers. Acta Chir. Plast.1983; 25: 229-238.

  13. Hubacek J, Hlozek Z. Non-invasive Lasertherapy. Otorhinolaryngology. 1984: 72-86.

  14. Hubacek J.: Experience with the Use of LLLT in ENT Medicine. Laser Partner 2000; No. 22.

  15. Karabaev E, Nasretdinov T et al. Laser therapy use in the treatment of recurrent purulent otitides media / Theses of International Symposium of Laser surgery and Laser medicine. Part II - Samarkand 1988, p. 231-233.

  16. Kim JB, Jung JY, Ahn JC, Rhee CK, Oh YH. Preventive and Therapeutic Effects of Low Level Laser Irradiation on Gentamicin-Induced Vestibulotoxicity in Rat Utricles. Korean J Otolaryngol - Head Neck Surg. 2009 Jan; 52 (1):19-28. Korean.

  17. Korepanov V. Laser therapy in cardiology, otolaryngopathology and pulmonology. Moscow 1995, p. 23.

  18. Lukowicz M, Zalewski P, Bulatowicz I, Buszko K, Klawe JJ. The impact of laser irradiation on global stability in patients with vertebrobasilar insufficiency: a clinical report. Med Sci Monit. 2011 Sep;17(9):CR517-22. PMID: 21873949 [PubMed - in process]

  19. Mirvakili A, Mehrparvar A, Mostaghaci M, Mollasadeghi A, Mirvakili M, Baradaranfar M, Dadgarnia M, Davari M. Low level laser effect in treatment of patients with intractable tinnitus due to sensorineural hearing loss. J Lasers Med Sci. 2014 Spring;5(2):71-4. PMID: 25653802 [PubMed]

  20. Mishenkin N, Dashkevich Y et al. Treatment of the chronic purulent otitis media with Laser irradiation energy / Regional scientific-practical conference and scientific session of Moscow Scientific Research Institute of ear, throat and nose - Rostov-on-Don 1979, 110-111.

  21. Mueller-Kortkramp M. An alternative therapy for Tinnitus by combining the power of the impulse laser with ginkgo-extract (EGb 761). Oral presentation at Neurootologic and Equilibriometric Societies Tinnitus-Seminar at the METRC, N.Y., USA, 29 June, 1999.

  22. Okhovat A, Berjis N, Okhovat H, Malekpour A, Abtahi H. Low-level laser for treatment of tinnitus: a self-controlled clinical trial. J Res Med Sci. 2011 Jan;16(1):33-8. PMID: 21448380 PMCID: PMC3063436.

  23. Olivier J, Plath P. Combined low power laser therapy and extracts of Ginkgo biloba in a blind trial of treatment for tinnitus. Laser Therapy 1993; 5 (3): 137-139.

  24. Plewka C, Dejakum K, Piegger J, Gunkel A, Thumfart W, Göbel G, Freysinger W. Behandlung von Tinnitus mit Medium-Level Laser. Studienergebnisse. Österreichischer HNO-Kongress. 2005, s 48, V018.

  25. Pluzhnikov M, Lopotko A, Gagauz A. Lasery v Rinofaringologii, Kishinev, Shtiinca 1991; 157.

  26. Procházka M, Tejnska R. Noninvasive laser therapy of tinnitus: In: A window on the laser medicine world. Proc. SPIE. 1999. Vol. 4166: 223-223.

  27. Procházka M, Tejnska R. Noninvasive laser therapy of tinnitus. Laser Partner, 2000; 4.

  28. Procházka M. Case Histories of Patients Suffering from Tinnitus Treated by Comprehensive Rehabilitation Therapy Including LLLT. Laser Partner, 2001; 48.

  29. Procházka M, Hahn A. Comprehensive laser rehabilitation therapy of tinnitus: long term double blind study in a group of 200 patients in three years. Laser Partner, 2002; 51.

  30. Procházka M. The Role of LLLT in Treatment of Tinnitus. Laser Partner, 2003; 61.

  31. Quittner M. Low Level Laser Therapy for Reduction of Tinnitus Symptoms. Swedish Laser Medical Society, Laser World, Guest Editorial, 2004.

  32. Rhee C, Lim E, Kim Y, Chung Y, Jung J, Chung P. Effect of low level laser (LLL) on cochlear and vestibular inner ear including tinnitus. Progress in biomedical optics and imaging 2006; 7 (1).

  33. Rhee CK, He P, Jung JY, Ahn JC, Chung PS, Suh MW. Effect of low-level laser therapy on cochlear hair cell recovery after gentamicin-induced ototoxicity. Lasers Med Sci. 2011 Dec 4. [Epub ahead of print] PMID: 22138884

  34. Rhee CK, Bahk CW, Kim SH, Ahn JC, Jung JY, Chung PS, Suh MW. Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma. J Biomed Opt. 2012 Jun;17(6):068002. PMID: 22734788 [PubMed - in process]

  35. Salahaldin AH, Abdulhadi K, Najjar N, Bener A. Low-level laser therapy in patients with complaints of tinnitus: a clinical study. ISRN Otolaryngol. 2012 Apr 9;2012:132060. doi: 10.5402/2012/132060. Print 2012. PMID: 23724264 [PubMed]

  36. Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F. Infrared light excites cells by changing their electrical capacitance. Nat Commun. 2012 Mar 13;3:736. doi: 10.1038/ncomms1742. PMID: 22415827

  37. Shiomi Y. Effect of low power laser irradiation on inner ear. Pract Otol (Kyoto). 1994; 87: 1135-1140.

  38. Swoboda R, Schott A. Behandlung neurologischer erkrankungen mit Ginkgo biloba Hevert®, Hyperforat® und Low-Power-Laser-Therapie. Medizinische Akademie Erfurt, Klinik und Poliklinik für Hals-, Nasen- und Ohrenerkrankungen. 1992.

  39. Tauber S, Beyer W, Baumgartner R E. al. Low-Level-Lasertherapie des Innenohres: eine dosimetrische Analyse der menschlichen Cochlea. Lasermedizin. 1998; 13 (3-4): 122.

  40. Tauber S et al. Double blind study for Low Level Laser Therapy in patients with chronic cochlear dysfunction. Dept. of Otolaryngology, Head and Neck Surgery, Laser-Forschungslabor, LIFE-Zentrum, Clinic of the University Munich, Germany.

  41. Thabit MN, Fouad N, Shahat B, Youssif M. Neurorehabil Neural Repair. 2015 Mar;29(3):224-33. doi: 10.1177/1545968314542616. Epub 2014 Jul 15. Combined central and peripheral stimulation for treatment of chronic tinnitus: a randomized pilot study. PMID: 25030898 [PubMed - in process]

  42. Wang F, Wang Z. Observation on clinical effect of 70 cases of acute otitis media treated by He-Ne laser irradiation on acupoints. Chin J Acupunct Moxibustion. 1991; 4 (1): 30-33.

  43. Wilden L, Dindinger D. Treatment of chronic diseases of the inner ear with low level laser therapy (LLLT). Laser Therapy, 1996; 8: 209-212.

  44. Wilden L, Ellerbrock D. Amelioration of the hearing capacity by low-level-laser-light (LLLL). Lasermedizin. 1999; 14: 129-138.

  45. Wilden L. Zur Wirkung von Low Level Laser Strahlung auf den zellulären Energietransfer. Laser Medizin. Volume 15, 1999/2000, No. 1-2.

Other scientific material supporting LASER treatment
of the inner ear and its diseases and disorders

  1. Andersen F, Deterville G. Evaluation of dysfunction grade using Soft Laser. IHA-GfK AG, Hergiswil, 2005: 9405696/1013051.

  2. Juberg R. Molde-model - a pilot study on tinnitus treatment with Low Level Laser Therapy in combination with holistic therapy. Material published at Tinnituskontakt i More og Romsdal & Kristiansund og Omegn Horselforening. Molde, Norway. 2003.

  3. Kolaylioglu A. Healing of Perforated Tympanic Membrane, Evidence material published on the internet. www.laser.nu/tlc.

  4. Marti P. Treatment through otolaser in combination with magnetic field therapy and oxygen-multistep-therapy. Cosmopolitan University & Universidad autonomo Gabriel Rene Moreno, Santa Cruz, Bolivia. 2001. Material published on the Internet.

  5. Myrhaug H. The theory of otosclerosis and Morbus Ménière (Labyrinthine vertigo) being caused by the same mechanism: physical irritants, an otognathic syndrome. Bergmanns Boktryckeri A/S, Bergen, Norway. 1981.

  6. Wilden L, Fritsch M. Tinnitus lindern durch Laserlicht. Werner Joop Verlag 1994/95/96/97, ISBN 3-926955-70-8.

  7. Wilden L. The effect of low level laser light on inner ear diseases. In: Low Level Laser Therapy. Clinical Practice and Scientific Background. Eds. Jan Tunér, Lars Hode. Prima Books in Sweden AB (1999). ISBN 91-630-7616-0.

  8. Wilden L. Results of patient survey conducted on more than 3000 patients over 13 years. Private Practice Dr. Wilden, Kurallee 16, 94072 Bad Füssing, Germany.

  9. Witt U, Felix C. Selective photo-biochemo-therapy in the combination of laser and ginkgo plant extracts acc. to the Witt method. Personal communication, 1989.

  10. Witt U. New alternative therapy against disorders of inner ear by combining the power of impuls-laser with ginkgo-extract (EGb 761). Material published on the Internet. 1996.

  11. Yong W, Young S, Ahn J, Chung P, Rhee C. Effect of low level laser on ototoxicity prevention of FM1-43 in postnatal organotypic culture of rat utricles. Progress in biomedical optics and imaging. 2007; 8 (1): Notes: 6424.

  12. Zachrisson B. Tinnitus treatment with laser in combination with pulsed electromagnetic field therapy. Summary published on the Internet, 2004.

  13. Zazzio M. Light penetration of the tissue of the hearing organ on pig irradiating with a 650 nm LASER light probe from outside the tympanic membrane. Photographic evidence material published on the Internet in November 2006 at www.alir.nu/medicin.

Scientific support for LASER treatment of somatosensory tinnitus

  1. Bertolucci L, Grey T. Clinical analysis of Mid-laser versus placebo treatment of arthralgic TMJ degenerative joints. J Craniomandib Practice. 1995; 13 (1): 26-29.

  2. Bezuur N, Hansson T. The effect of therapeutic laser treatment in patients with craniomandibular disorders. J Craniomandibular Disorders. 1988; 2: 83-86.

  3. Bjordal J, Couppé C, Chow R, Tunér J, Ljunggren E. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother. 2003; 49 (2): 107-116. Review.

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